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2026 Artemetrx State of Specialty Spend and Trend Report

PSG announces the results of the industry’s go-to report on specialty drug spend and trend.

With specialty drug costs remaining a top concern and a pipeline bursting with breakthrough therapies, payers can’t afford to manage specialty spend with yesterday’s strategies. The 2026 Artemetrx State of Specialty Spend and Trend Report delivers the critical data you need to stay ahead of the curve.

Special Thanks to Our Sponsor

Key Findings

  • Specialty Drug Trend: Specialty drug trend remains high but decreased from 12.2% to 10.8% on a gross cost basis
  • Drivers of Specialty Drug Trend: Claim utilization is now the dominant driver of specialty drug trend as the percentage of members using specialty drugs rose to 5.5%
  • Top Specialty Drugs by Spend: Humira exited the top 10 specialty drugs by spend as Skyrizi, Dupixent, and Rinvoq climbed up the list
  • Biosimilars Market Share: The market share for biosimilars grew from 32.2% to 56.3%, led by the impact of Humira and Stelara biosimilars
  • Non-Specialty Drug Spend and Trend: Spotlight feature reveals 10.4% trend in non-specialty, driven by the diabetes category and GLP-1 medications

Preview the 2026 State of Specialty Spend and Trend Report

About the Researchers

Morgan Lee

Morgan Lee, PhD, MPH, CPH

Morgan Lee is a dynamic behavioral scientist and research leader with over 15 years of quantitative and qualitative research and evaluation experience in health…
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Mike Lonergan, RPh

At PSG, Mike leads with a simple, powerful philosophy: enable, support, and develop people while solving the problems that matter most for clients. He champions transparency,…
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Renee Rayburg, RPh

Renee Rayburg brings almost 40 years of experience in the pharmaceutical industry. At PSG, Renee leads clinical strategy for payer clients, developing solutions that…
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Kelly Dean, MBA

Kelly Dean has more than 20 years of analytical and technical experience, with proven proficiency in data extraction, business intelligence, and business software tools.
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Kristy Scheinfeldt, MBA

Kristy Scheinfeldt has 16 years of clinical and data analytics experience. Prior to joining PSG, Kristy was Associate Director, Clinical Analytics for OptumRx, where she designed,…
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